India holds an unassailable 2-0 lead in the three-match ODI series against Afghanistan.
Captain Shubman Gill has been in prolific form, averaging 93.25 across five ODIs this year.
Pace-bowling all-rounder Harshit Rana returns to the squad after completing his injury rehabilitation.
Despite previous challenges, Afghanistan aims for a consolation win at the historic MA Chidambaram Stadium.